I'd like to see a Via-based AMD motherboard with PCI Express slots on it so I can TRY a Parhelia AVPe.
Also - and I know I mention this every time we talk about Matrox - I'd love to see a sub-$100 part from them. So much of what I do nowadays is onboard video or $50-ish low-end ATI cards. I'd really like to have something more compelling, along the lines of the G100/G200, at that lower price point.
If it's a 2-year-old design surely they've found a way to make a cheaper version!